Immune-mediating necrotizing myopathy (IMNM) is a debilitating disease that causes the muscles to weaken.

This can lead to difficulties in everyday life, like problems with walking, standing, or lifting. Here are some more important facts about IMNM:

IMNM causes extreme weakness in the muscles, especially in the upper legs and neck.

People with IMNM may also have some muscular pain. Here are some signs of IMNM to watch
out for:

  • Feeling tired after walking or standing
  • Tripping or falling
  • Difficulty swallowing or breathing
  • Difficulty getting up from low chairs, climbing stairs, or lifting objects
  • Weight loss
  • Difficulty combing hair

If your doctor suspects IMNM, they may order a test to check for certain antibodies in your blood.

Your doctor may also perform a biopsy—a test that requires removing a small piece of muscle tissue for further examination.

Current treatments for IMNM are non-specific and inadequate.

At the moment, there are no treatments that are approved by the FDA for IMNM. Doctors use a few different medications to treat IMNM, but they were not developed for the disease, and they come with many side effects.

Patients deserve a more targeted therapy.

We believe that patients with IMNM need a treatment specifically designed to target the cause of their disease. That’s why we are researching a potential treatment that stops the complement process before it continues to kill muscle cells.